![Frontiers | Therapeutic Implications of Tumor Microenvironment in Lung Cancer: Focus on Immune Checkpoint Blockade Frontiers | Therapeutic Implications of Tumor Microenvironment in Lung Cancer: Focus on Immune Checkpoint Blockade](https://www.frontiersin.org/files/Articles/799455/fimmu-12-799455-HTML-r1/image_m/fimmu-12-799455-g001.jpg)
Frontiers | Therapeutic Implications of Tumor Microenvironment in Lung Cancer: Focus on Immune Checkpoint Blockade
![Frontiers | Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E Frontiers | Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E](https://www.frontiersin.org/files/MyHome%20Article%20Library/370030/370030_Thumb_400.jpg)
Frontiers | Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E
![Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy | Journal for ImmunoTherapy of Cancer Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy | Journal for ImmunoTherapy of Cancer](https://jitc.bmj.com/content/jitc/10/2/e004089/F1.large.jpg)
Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy | Journal for ImmunoTherapy of Cancer
![CD73 is a hypoxia-responsive gene and promotes the Warburg effect of human gastric cancer cells dependent on its enzyme activity CD73 is a hypoxia-responsive gene and promotes the Warburg effect of human gastric cancer cells dependent on its enzyme activity](https://www.jcancer.org/v12/p6372/toc.jpg)
CD73 is a hypoxia-responsive gene and promotes the Warburg effect of human gastric cancer cells dependent on its enzyme activity
![Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers](https://pub.mdpi-res.com/cancers/cancers-14-05663/article_deploy/html/images/cancers-14-05663-ag.png?1669095106)
Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers
![Ecto‐5′‐nucleotidase (CD73) is a potential target of hepatocellular carcinoma - Shali - 2019 - Journal of Cellular Physiology - Wiley Online Library Ecto‐5′‐nucleotidase (CD73) is a potential target of hepatocellular carcinoma - Shali - 2019 - Journal of Cellular Physiology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/e787e1a1-b85a-4338-91b1-863bf3374528/jcp27694-gra-0001-m.jpg?trick=1676271251498)
Ecto‐5′‐nucleotidase (CD73) is a potential target of hepatocellular carcinoma - Shali - 2019 - Journal of Cellular Physiology - Wiley Online Library
![Single Cell Spatial Analysis Reveals the Topology of Immunomodulatory Purinergic Signaling in Glioblastoma | bioRxiv Single Cell Spatial Analysis Reveals the Topology of Immunomodulatory Purinergic Signaling in Glioblastoma | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2022/01/12/2022.01.12.475925/F1.large.jpg)
Single Cell Spatial Analysis Reveals the Topology of Immunomodulatory Purinergic Signaling in Glioblastoma | bioRxiv
![Molecular principles of metastasis: a hallmark of cancer revisited | Signal Transduction and Targeted Therapy Molecular principles of metastasis: a hallmark of cancer revisited | Signal Transduction and Targeted Therapy](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41392-020-0134-x/MediaObjects/41392_2020_134_Fig1_HTML.png)
Molecular principles of metastasis: a hallmark of cancer revisited | Signal Transduction and Targeted Therapy
![Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers](https://pub.mdpi-res.com/cancers/cancers-14-05663/article_deploy/html/images/cancers-14-05663-g003.png?1669095088)
Cancers | Free Full-Text | Identification of CD73 as a Novel Biomarker Encompassing the Tumor Microenvironment, Prognosis, and Therapeutic Responses in Various Cancers
![Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer - ScienceDirect Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0168365921003643-ga1.jpg)
Cancer-cell-biomimetic Upconversion nanoparticles combining chemo-photodynamic therapy and CD73 blockade for metastatic triple-negative breast cancer - ScienceDirect
![CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model | BMC Cancer | Full Text CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model | BMC Cancer | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12885-020-06893-3/MediaObjects/12885_2020_6893_Fig3_HTML.png)
CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model | BMC Cancer | Full Text
![CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells - ScienceDirect CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2213671118301000-fx1.jpg)
CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells - ScienceDirect
![CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis | Journal of Hematology & Oncology | Full Text CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis | Journal of Hematology & Oncology | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs13045-019-0724-7/MediaObjects/13045_2019_724_Fig7_HTML.png)
CD73 promotes hepatocellular carcinoma progression and metastasis via activating PI3K/AKT signaling by inducing Rap1-mediated membrane localization of P110β and predicts poor prognosis | Journal of Hematology & Oncology | Full Text
![CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer | Cell Death & Disease CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer | Cell Death & Disease](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41419-020-2403-6/MediaObjects/41419_2020_2403_Fig1_HTML.png)
CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer | Cell Death & Disease
![PDF] Prognositic value of CD73-adenosinergic pathway in solid tumor: A meta-analysis and systematic review. | Semantic Scholar PDF] Prognositic value of CD73-adenosinergic pathway in solid tumor: A meta-analysis and systematic review. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/2538dfb30daa57e7af8664d62d1fce4b79216bdd/2-Figure1-1.png)
PDF] Prognositic value of CD73-adenosinergic pathway in solid tumor: A meta-analysis and systematic review. | Semantic Scholar
![The difference of CD73 expression levels in lung cancer tumor tissue... | Download Scientific Diagram The difference of CD73 expression levels in lung cancer tumor tissue... | Download Scientific Diagram](https://www.researchgate.net/publication/356286499/figure/fig1/AS:1093933165756416@1637825399406/The-difference-of-CD73-expression-levels-in-lung-cancer-tumor-tissue-and-non-tumor.png)
The difference of CD73 expression levels in lung cancer tumor tissue... | Download Scientific Diagram
![CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model | BMC Cancer | Full Text CD73 blockade enhances the local and abscopal effects of radiotherapy in a murine rectal cancer model | BMC Cancer | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12885-020-06893-3/MediaObjects/12885_2020_6893_Fig2_HTML.png)